Review Paper on TPIAT:
Total pancreatectomy and islet autotransplantion for chronic and recurrent acute pancreatitis
Kendall R. McEachron, Melena D. Bellin
Curr Opin Gastroenterol. 2018 Sep; 34(5): 367–373. PMCID: PMC9623823
Selected Other Research Publications on TPIAT from the University of Minnesota:
Peri-Transplant Inflammation and Long-Term Diabetes Outcomes Were Not Impacted by Either Etanercept or Alpha-1-Antitrypsin Treatment in Islet Autotransplant Recipients
Abdel-Karim TR, Hodges JS, Herold KC, Pruett TL, Ramanathan KV, Hering BJ, Dunn TB, Kirchner VA, Beilman GJ, Bellin MD. Peri-Transplant Inflammation and Long-Term Diabetes Outcomes Were Not Impacted by Either Etanercept or Alpha-1-Antitrypsin Treatment in Islet Autotransplant Recipients. Transpl Int. 2024 Jan 31;37:12320. PMID: 38357216; PMCID:PMC10864605.
How Durable Is Total Pancreatectomy and Intraportal Islet Cell Transplantation for Treatment of Chronic Pancreatitis?
Melena D Bellin, Gregory J Beilman, David ER Sutherland, Hawa Ali, Arzu Petersen, Steven Mongin, Varvara Kirchner, Sarah J Schwarzenberg, Guru Trikudanathan, Martin L Freeman, Timothy L Pruett, Srinath Chinnakotla
J Am Coll Surg. Author manuscript; available in PMC 2021 Nov 10. J Am Coll Surg. 2019 Apr; 228(4): 329–339. PMCID: PMC8579321.
Early Metabolic Measures Predict Long-term Insulin Independence in Recipients of Total Pancreatectomy and Islet Autotransplantation
Yoshihide Nanno, James S. Hodges, Martin L. Freeman, Guru Trikudanathan, Sarah J. Schwarzenberg, Elissa M. Downs, Karthik Ramanathan, Timothy L. Pruett, Gregory J. Beilman, Srinath Chinnakotla, Bernhard J. Hering, Melena D. Bellin
Transplant Direct. 2024 Jan; 10(1): e1561. Published online 2023 Dec 12. PMCID: PMC10715795.
A randomized controlled pilot trial of etanercept and alpha-1 antitrypsin to improve autologous islet engraftment
Tasneem R. Abdel-karim, James S. Hodges, Timothy L. Pruett, Karthik V. Ramanathan, Bernhard J. Hering, Ty B. Dunn, Varvara A. Kirchner, Gregory J. Beilman, Melena D. Bellin
Pancreatology. 2023 Jan; 23(1): 57–64. Published online 2022 Nov 24. PMCID: PMC9839597.
Decreased Intestinal Microbiota Diversity is Associated With Increased Gastrointestinal Symptoms in Patients With Chronic Pancreatitis
Kendall R. McEachron, Harika Nalluri, Gregory J. Beilman, Varvara A. Kirchner, Timothy L. Pruett, Martin L. Freeman, Guru Trikudanathan, Christopher Staley, Melena D. Bellin
Pancreas. 2022 Jul 1; 51(6): 649–656. Published online 2022 Sep 13. PMCID: PMC9547966.
Surgical approach and short-term outcomes in adults and children undergoing total pancreatectomy with islet autotransplantation: A report from the Prospective Observational Study of TPIAT
Jaimie D. Nathan, Yi Yang, Anne Eaton, Piotr Witkowski, Martin Wijkstrom, Matthew Walsh, Guru Trikudanathan, Vikesh K. Singh, Sarah J. Schwarzenberg, Timothy L. Pruett, Andrew Posselt, Bashoo Naziruddin, Sri Prakash Mokshagundam, Katherine Morgan, Luis F. Lara, Varvara Kirchner, Jin He, Timothy B. Gardner, Martin L. Freeman, Kate Ellery, Darwin L. Conwell, Srinath Chinnakotla, Gregory J. Beilman, Syed Ahmad, Maisam Abu-El-Haija, James S. Hodges, Melena D. Bellin
Pancreatology. 2022 Jan; 22(1): 1–8. Published online 2021 Sep 29. PMCID: PMC8748311.
Reduced Bone Mineral Density in the First Year After Total Pancreatectomy with Islet Autotransplantation (TPIAT)
Jillian K. Wothe, Robert Aidoo, Kendall R. McEachron, Tasma Harindhanavudhi, Guru Trikudanathan, Martin L. Freeman, Varvara Kirchner, Timothy L. Pruett, Gregory J. Beilman, James S. Hodges, Melena D. Bellin
Pancreatology. 2021 Dec; 21(8): 1491–1497. Published online 2021 Sep 4. PMCID: PMC8629939.
Type 1 diabetes mellitus in patients with recurrent acute and chronic pancreatitis: a case series
Harmeet K. Kharoud, Tetyana Mettler, Martin L. Freeman, Guru Trikudanathan, Gregory J. Beilman, Srinath Chinnakotla, Elissa Downs, Sarah J. Schwarzenberg, Melena D. Bellin
Pancreatology. 2021 Jan; 21(1): 95–97. Published online 2020 Dec 6. doi: 10.1016/j.pan.2020.12.006 PMCID: PMC7856006.
Preoperative ERCP has no impact on islet cell yield following total pancreatectomy and islet transplantation (TPIAT): Results from the Prospective Observational Study of TPIAT (POST) cohort
Guru Trikudanathan, B. Joseph Elmunzer, Yi Yang, Maisam Abu-El-Haija, David Adams, Syed Ahmad, Appakalai N. Balamurugan, Gregory J. Beilman, Srinath Chinnakotla, Darwin L. Conwell, Martin L. Freeman, Timothy B. Gardner, Betul Hatipoglu, James S. Hodges, Varvara Kirchner, Luis F. Lara, Leslie Long-Simpson, Rebecca Mitchell, Katherine Morgan, Jaimie D. Nathan, Bashoo Naziruddin, Andrew Posselt, Timothy L. Pruett, Sarah J. Scwarzenberg, Vikesh K. Singh, Kerrington Smith, Martin Wijkstrom, Piotr Witkowski, Melena D. Bellin
Pancreatology. 2021 Jan; 21(1): 275–281. Published online 2020 Nov 24. doi: 10.1016/j.pan.2020.11.008 PMCID: PMC7924984.
Alterations in Enteroendocrine Hormones After Total Pancreatectomy With Islet Autotransplantation
Pancreas. Author manuscript; available in PMC 2021 Jul 1. PMCID: PMC7321866
Utility of arginine stimulation testing in preoperative assessment of children undergoing total pancreatectomy with islet autotransplantation
Kendall R. McEachron, Mariya E. Skube, Yi Yang, James S. Hodges, Joshua Wilhelm, Gregory Beilman, Srinath Chinnakotla, Sarah J. Schwarzenberg, Melena D. Bellin
Clin Transplant. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Clin Transplant. 2019 Aug; 33(8): e13647. Published online 2019 Jul 4. doi: 10.1111/ctr.13647 PMCID: PMC7041967.
Islet Graft Function Is Preserved After Pregnancy in Patients With Previous Total Pancreatectomy With Islet Autotransplant
Mariya E. Skube, Pamela D. Mills, James S. Hodges, Greg J. Beilman, Melena D. Bellin
Pancreas. Author manuscript; available in PMC 2019 Jul 3.
Published in final edited form as: Pancreas. 2018 Oct; 47(9): e64–e65. doi: 10.1097/MPA.0000000000001129 PMCID: PMC6609149.
Psychiatric Comorbidities in Patients Undergoing Total Pancreatectomy With Islet Cell Autotransplantation and Associated Mortality
Kendall R. McEachron, Mary Melton, Gregory J. Beilman, Melena D. Bellin
Pancreas. Author manuscript; available in PMC 2022 Nov 10.
Published in final edited form as: Pancreas. 2018 Apr; 47(4): e16–e18. doi: 10.1097/MPA.0000000000001010 PMCID: PMC9648619.
Accuracy of Continuous Glucose Monitoring in Patients After Total Pancreatectomy with Islet Autotransplantation
Gregory P. Forlenza, Brandon M. Nathan, Antoinette Moran, Ty B. Dunn, Gregory J. Beilman, Timothy L. Pruett, Boris P. Kovatchev, Melena D. Bellin
Diabetes Technol Ther. 2016 Aug 1; 18(8): 455–463. Published online 2016 Aug 1. doi: 10.1089/dia.2015.0405 PMCID: PMC4991614.
Preoperative Computerized Tomography and Magnetic Resonance Imaging of the Pancreas Predicts Pancreatic Mass and Functional Outcomes After Total Pancreatectomy and Islet Autotransplant
Michael C. Young, Jake R. Theis, James S. Hodges, Ty B. Dunn, Timothy L. Pruett, Srinath Chinnakotla, Sidney P. Walker, Martin L. Freeman, Guru Trikudanathan, Mustafa Arain, R. Paul Robertson, Joshua J. Wilhelm, Sarah J. Schwarzenberg, Barbara Bland, Gregory J. Beilman, Melena D. Bellin
Pancreas. Author manuscript; available in PMC 2017 Aug 1.
Published in final edited form as: Pancreas. 2016 Aug; 45(7): 961–966. doi: 10.1097/MPA.0000000000000591 PMCID: PMC4936953.
Metastatic Pancreatic Adenocarcinoma After Total Pancreatectomy Islet Autotransplantation for Chronic Pancreatitis
S. Muratore, X. Zeng, M. Korc, S. McElyea, J. Wilhelm, M. Bellin, G. Beilman
Am J Transplant. Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: Am J Transplant. 2016 Sep; 16(9): 2747–2752. Published online 2016 Jun 27. doi: 10.1111/ajt.13851 PMCID: PMC5007168.
Pancreatogenic Diabetes in Children With Recurrent Acute and Chronic Pancreatitis: Risks, Screening, and Treatment (Mini-Review)
Melena D. Bellin
Front Pediatr. 2022; 10: 884668. Published online 2022 Apr 26. PMCID: PMC9086714.
The above articles are externally sourced and were published prior to current ADA guidelines. If you would like accessible versions of any of the above documents, please email [email protected].